Objectives: The incidence of dementia is increasing in the developing world in tandem with the ageing population. By 2034, 1/5th of the Tunisian population will be aged of 65 years and older. The number of Alzheimer’s Disease (AD) patients in Tunisia was estimated at 35.000 by now. This number will reach about 60.000 patients in 2020. The necessity to adapt our dementia setting care, led us to create the first AD center in TunisiThe project was initially presented in Cyprus in the 5th International Conference on Alzheimer’s Disease and Related Disorders in the Middle East in 2009. Objectives: To detail the concept and to evaluate the usefulness of such dedicated centers in the dementia care. Methods: The project was axed on the early diagnosis and assessment, the appropriate medical and social care for patients and their careers and the promotion of research in this field. The building concept integrated, in a unique place, the three major dementia’s care axes: early diagnosis, daily medical care and research. The project has been entirely funded by donors. Results: About 1800 demented patients are listed in our records. More than 700 of them have been seen in the daycare unit since the beginning of the AD Center’s activities in September 2010. Hence, the center offers for patients affected by dementia and their families: early diagnosis, medical management and information about the disease. At the same time, it gives professionals the opportunity to translate research advances into improved care for patients and to efficiently help families cope with the effects of the disease. Finally, it provides a network that contributes to enhance research and to train students and healthcare providers from many different disciplines. Conclusions: We are facing new both medical and social problem for demented patients in our countries: healthcare professionals are not ready to early diagnose in addition to the low social awareness and underestimation of the problem from governmental bodies. This center constituted only a first answer while Tunisia faces a huge public health problem with dementiOur aim is to integrate this pilot project into a national and global action plan covering the need of all demented patients.